Physico-chemical studies of resveratrol, methyl-jasmonate and cyclodextrin interactions: an approach to resveratrol bioproduction optimization

E. Oliva , D. Mathiron (1) , E. Bertaut , David Landy (2) , D. Cailleu (1) , S. Pilard (1) , C. Clément (3) , E. Courot (3) , V. Bonnet , F. Djedaïni-Pilard (4)

1 PFA - Plateforme Analytique - UPJV
2 UCEIV - Unité de Chimie Environnementale et Interactions sur le Vivant
3 RIBP - Résistance Induite et Bioprotection des Plantes - EA 4707
4 LG2A - Laboratoire de Glycochimie, des Antimicrobiens et des Agro-ressources - UMR CNRS 7378

trans-Resveratrol (RSV) is a natural phenolic molecule of the stilbene family known for its anti-oxidant properties in the field of nutraceuticals and cosmetics. Its production by grapevine cell suspensions is induced by the addition to the culture medium of elicitor compounds, methyl jasmonate (MeJA) and cyclodextrins (CDs). Physico-chemical studies were performed to understand the mechanism of action of CDs on this bioproduction of RSV. Inclusion complexes of RSV in CDs were first observed and then interactions with MeJA were identified using various analytical techniques such as UV and nuclear magnetic resonance (NMR) spectroscopies, mass spectrometry (MS) and isothermal titration calorimetry (ITC).

Domaines: Sciences du Vivant [q-bio]

E. Oliva, D. Mathiron, E. Bertaut, David Landy, D. Cailleu, et al.. Physico-chemical studies of resveratrol, methyl-jasmonate and cyclodextrin interactions: an approach to resveratrol bioproduction optimization. RSC Advances, 2018, 8 (3), pp.1528-1538. ⟨10.1039/C7RA11619E⟩. ⟨hal-02944756⟩