Atlas of Genetics and Cytogenetics in Oncology and Haematology in 2013

Jean-Loup Huret (1, 2) , Mohammad Ahmad (2) , Mélanie Arsaban (2) , Alain Bernheim (3, 4) , Jérémy Cigna (2) , François Desangles (5, 2) , Jean-Christophe Guignard (2) , Marie-Christine Jacquemot-Perbal (6) , Maureen Labarussias (2) , Vanessa Leberre (2) , Anne Malo (2) , Catherine Morel-Pair (6) , Hossein Mossafa (2, 7) , Jean-Claude Potier (8) , Guillaume Texier (8) , Franck Viguié (9, 2) , Sylvie Yau Chun Wan-Senon (2) , Alain Zasadzinski (6) , Philippe Dessen (4, 3)

1 Service de Génétique Médicale [CHU Poitiers]
2 Atlas Poitiers
3 U985 - Génétique des tumeurs
4 IGR - Institut Gustave Roussy
5 Hôpital d'Instruction des Armées du Val de Grâce
6 INIST - Institut de l'information scientifique et technique
7 Laboratoire CERBA [Saint Ouen l'Aumône]
8 CRITT Informatique
9 CISA - Cytométrie et Imagerie Saint-Antoine

The Atlas of Genetics and Cytogenetics in Oncology and Haematology (http://AtlasGeneticsOncology.org) is a peer-reviewed internet journal/encyclopaedia/database focused on genes implicated in cancer, cytogenetics and clinical entities in cancer and cancer-prone hereditary diseases. The main goal of the Atlas is to provide review articles that describe complementary topics, namely, genes, genetic abnormalities, histopathology, clinical diagnoses and a large iconography. This description, which was historically based on karyotypic abnormalities and in situ hybridization (fluorescence in situ hybridization) techniques, now benefits from comparative genomic hybridization and massive sequencing, uncovering a tremendous amount of genetic rearrangements. As the Atlas combines different types of information (genes, genetic abnormalities, histopathology, clinical diagnoses and external links), its content is currently unique. The Atlas is a cognitive tool for fundamental and clinical research and has developed into an encyclopaedic work. In clinical practice, it contributes to the cytogenetic diagnosis and may guide treatment decision making, particularly regarding rare diseases (because they are numerous and are frequently encountered). Readers as well as the authors of the Atlas are researchers and/or clinicians.

Mots clés: oncology; haematology; internet journal; database

Domaines: Sciences de l'information et de la communication; Sciences du Vivant [q-bio]; Base de données [cs.DB]

Jean-Loup Huret, Mohammad Ahmad, Mélanie Arsaban, Alain Bernheim, Jérémy Cigna, et al.. Atlas of Genetics and Cytogenetics in Oncology and Haematology in 2013. Nucleic Acids Research, 2013, 41 (D1), pp.D920-D924. ⟨10.1093/nar/gks1082⟩. ⟨hal-01587507⟩