<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-01571987</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-19T11:54:01+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="fr">Dioxines dans l'environnement : quels risques pour la santé ?</title>
            <author role="aut">
              <persName>
                <forename type="first">Sophie</forename>
                <surname>Alexander</surname>
              </persName>
              <idno type="halauthorid">442019-0</idno>
              <affiliation ref="#struct-345801"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Denis</forename>
                <surname>Bard</surname>
              </persName>
              <idno type="halauthorid">485138-0</idno>
              <affiliation ref="#struct-310969"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Robert</forename>
                <surname>Barouki</surname>
              </persName>
              <email type="md5">3738f3ce7cf366090fac6973dfbb3f44</email>
              <email type="domain">parisdescartes.fr</email>
              <idno type="idhal" notation="numeric">1183338</idno>
              <idno type="halauthorid" notation="string">359128-1183338</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-9471-399X</idno>
              <idno type="IDREF">https://www.idref.fr/061063266</idno>
              <idno type="VIAF">https://viaf.org/viaf/211852213</idno>
              <idno type="ISNI">http://isni.org/isni/0000000432133932</idno>
              <affiliation ref="#struct-2865"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Frédéric Yves</forename>
                <surname>Bois</surname>
              </persName>
              <email type="md5">b6ca7fd2d64eaa3f39ff877701a1acbd</email>
              <email type="domain">ineris.fr</email>
              <idno type="idhal" notation="numeric">954634</idno>
              <idno type="halauthorid" notation="string">1208798-954634</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/E-9241-2012</idno>
              <idno type="IDREF">https://www.idref.fr/033531749</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-4154-0391</idno>
              <affiliation ref="#struct-3186"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jacques</forename>
                <surname>Descotes</surname>
              </persName>
              <idno type="halauthorid">593174-0</idno>
              <affiliation ref="#struct-172478"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Marco</forename>
                <surname>Dujardin</surname>
              </persName>
              <idno type="halauthorid">1208799-0</idno>
              <affiliation ref="#struct-345801"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">André</forename>
                <surname>Guillouzo</surname>
              </persName>
              <idno type="halauthorid">477496-0</idno>
              <affiliation ref="#struct-14031"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Cédric</forename>
                <surname>Hermans</surname>
              </persName>
              <idno type="halauthorid">1208796-0</idno>
              <affiliation ref="#struct-92863"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Gérard</forename>
                <surname>Keck</surname>
              </persName>
              <idno type="halauthorid">624705-0</idno>
              <affiliation ref="#struct-300422"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Manolis</forename>
                <surname>Kogevinas</surname>
              </persName>
              <idno type="idhal" notation="numeric">762958</idno>
              <idno type="halauthorid" notation="string">437615-762958</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-9605-0461</idno>
              <affiliation ref="#struct-74302"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jean-François</forename>
                <surname>Narbonne</surname>
              </persName>
              <idno type="halauthorid">978011-0</idno>
              <affiliation ref="#struct-683"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">François</forename>
                <surname>Perin</surname>
              </persName>
              <idno type="halauthorid">1208797-0</idno>
              <affiliation ref="#struct-301888"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">André</forename>
                <surname>Picot</surname>
              </persName>
              <idno type="halauthorid">286990-0</idno>
              <affiliation ref="#struct-440"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Thierry</forename>
                <surname>Pineau</surname>
              </persName>
              <email type="md5">631e2286abfe0daba9b67b300236c2f9</email>
              <email type="domain">inrae.fr</email>
              <idno type="idhal" notation="numeric">1202623</idno>
              <idno type="halauthorid" notation="string">155338-1202623</idno>
              <affiliation ref="#struct-74284"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jean-François</forename>
                <surname>Savouret</surname>
              </persName>
              <email type="md5">5eec0e683b3226ff98170a35081a2683</email>
              <email type="domain">parisdescartes.fr</email>
              <idno type="idhal" notation="numeric">834781</idno>
              <idno type="halauthorid" notation="string">160025-834781</idno>
              <idno type="IDREF">https://www.idref.fr/148649025</idno>
              <idno type="VIAF">https://viaf.org/viaf/173650750</idno>
              <idno type="ISNI">http://isni.org/isni/0000000123690049</idno>
              <affiliation ref="#struct-18712"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Colette</forename>
                <surname>ORANGE</surname>
              </persName>
              <email type="md5">0c062899cb8fb730849dcc323c30add0</email>
              <email type="domain">inist.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2017-08-04 11:10:42</date>
              <date type="whenModified">2026-04-10 14:18:03</date>
              <date type="whenReleased">2017-08-04 11:21:18</date>
              <date type="whenProduced">2000</date>
              <date type="whenEndEmbargoed">2017-08-04</date>
              <ref type="file" target="https://hal-lara.archives-ouvertes.fr/hal-01571987v1/document">
                <date notBefore="2017-08-04"/>
              </ref>
              <ref type="file" subtype="author" n="1" target="https://hal-lara.archives-ouvertes.fr/hal-01571987v1/file/INSERM_2000_dioxines.pdf" id="file-1571987-1625394">
                <date notBefore="2017-08-04"/>
              </ref>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="317116">
                <persName>
                  <forename>Colette</forename>
                  <surname>ORANGE</surname>
                </persName>
                <email type="md5">0c062899cb8fb730849dcc323c30add0</email>
                <email type="domain">inist.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-01571987</idno>
            <idno type="halUri">https://hal-lara.archives-ouvertes.fr/hal-01571987</idno>
            <idno type="halBibtex">alexander:hal-01571987</idno>
            <idno type="halRefHtml">[Rapport de recherche] Institut national de la santé et de la recherche médicale(INSERM). 2000, 406 p., références bibliographiques disséminées</idno>
            <idno type="halRef">[Rapport de recherche] Institut national de la santé et de la recherche médicale(INSERM). 2000, 406 p., références bibliographiques disséminées</idno>
            <availability status="restricted">
              <licence target="https://about.hal.science/hal-authorisation-v1/">HAL Authorization<ref corresp="#file-1571987-1625394"/></licence>
            </availability>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="INSERM">INSERM - Institut national de la santé et de la recherche médicale</idno>
            <idno type="stamp" n="INERIS">INERIS - Institut National de l'Environnement industriel et des RISques</idno>
            <idno type="stamp" n="UNIV-PARIS5" corresp="UNIV-PARIS">Université Paris Descartes (Paris 5)</idno>
            <idno type="stamp" n="HCL">Hospices Civils de Lyon</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="INRA">INRA - Institut national de la recherche agronomique</idno>
            <idno type="stamp" n="SANTE_PUB_INSERM" corresp="INSERM">Santé Publique à l'Inserm</idno>
            <idno type="stamp" n="FNCLCC" corresp="INSERM">UNICANCER</idno>
            <idno type="stamp" n="CURIE" corresp="INSERM">Institut Curie</idno>
            <idno type="stamp" n="GIP-BE">GIP Bretagne Environnement</idno>
            <idno type="stamp" n="ICSN">Collection des Publications de l'Institut de Chimie des Substances Naturelles, UPR2301, Gif sur Yvette</idno>
            <idno type="stamp" n="LARA">LARA</idno>
            <idno type="stamp" n="PSL">Université Paris sciences et lettres</idno>
            <idno type="stamp" n="UNIV-PARIS-SACLAY">Université Paris-Saclay</idno>
            <idno type="stamp" n="AGREENIUM">Archive ouverte en agrobiosciences</idno>
            <idno type="stamp" n="UNIV-PSUD-SACLAY" corresp="UNIV-PARIS-SACLAY">Université Paris Sud pour Paris Saclay</idno>
            <idno type="stamp" n="TEST-UNIV-RENNES">TEST Université de Rennes</idno>
            <idno type="stamp" n="UNIV-RENNES">Université de Rennes</idno>
            <idno type="stamp" n="EXPERTISESCOLLECTIVESINSERM" corresp="INSERM">Expertises collectives Inserm</idno>
            <idno type="stamp" n="INRAE">Institut National de Recherche en Agriculture, Alimentation et Environnement</idno>
            <idno type="stamp" n="UNIV-PARIS">Université Paris Cité</idno>
            <idno type="stamp" n="INSTITUT-CURIE-PSL" corresp="PSL">Institut Curie - PSL</idno>
            <idno type="stamp" n="GS-HEALTH-DRUG-SCIENCES">Graduate School Health and Drug Sciences</idno>
          </seriesStmt>
          <notesStmt>
            <note type="report" n="6">Research Report</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="fr">Dioxines dans l'environnement : quels risques pour la santé ?</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Sophie</forename>
                    <surname>Alexander</surname>
                  </persName>
                  <idno type="halauthorid">442019-0</idno>
                  <affiliation ref="#struct-345801"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Denis</forename>
                    <surname>Bard</surname>
                  </persName>
                  <idno type="halauthorid">485138-0</idno>
                  <affiliation ref="#struct-310969"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Robert</forename>
                    <surname>Barouki</surname>
                  </persName>
                  <email type="md5">3738f3ce7cf366090fac6973dfbb3f44</email>
                  <email type="domain">parisdescartes.fr</email>
                  <idno type="idhal" notation="numeric">1183338</idno>
                  <idno type="halauthorid" notation="string">359128-1183338</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-9471-399X</idno>
                  <idno type="IDREF">https://www.idref.fr/061063266</idno>
                  <idno type="VIAF">https://viaf.org/viaf/211852213</idno>
                  <idno type="ISNI">http://isni.org/isni/0000000432133932</idno>
                  <affiliation ref="#struct-2865"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Frédéric Yves</forename>
                    <surname>Bois</surname>
                  </persName>
                  <email type="md5">b6ca7fd2d64eaa3f39ff877701a1acbd</email>
                  <email type="domain">ineris.fr</email>
                  <idno type="idhal" notation="numeric">954634</idno>
                  <idno type="halauthorid" notation="string">1208798-954634</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/E-9241-2012</idno>
                  <idno type="IDREF">https://www.idref.fr/033531749</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-4154-0391</idno>
                  <affiliation ref="#struct-3186"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jacques</forename>
                    <surname>Descotes</surname>
                  </persName>
                  <idno type="halauthorid">593174-0</idno>
                  <affiliation ref="#struct-172478"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Marco</forename>
                    <surname>Dujardin</surname>
                  </persName>
                  <idno type="halauthorid">1208799-0</idno>
                  <affiliation ref="#struct-345801"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">André</forename>
                    <surname>Guillouzo</surname>
                  </persName>
                  <idno type="halauthorid">477496-0</idno>
                  <affiliation ref="#struct-14031"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Cédric</forename>
                    <surname>Hermans</surname>
                  </persName>
                  <idno type="halauthorid">1208796-0</idno>
                  <affiliation ref="#struct-92863"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Gérard</forename>
                    <surname>Keck</surname>
                  </persName>
                  <idno type="halauthorid">624705-0</idno>
                  <affiliation ref="#struct-300422"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Manolis</forename>
                    <surname>Kogevinas</surname>
                  </persName>
                  <idno type="idhal" notation="numeric">762958</idno>
                  <idno type="halauthorid" notation="string">437615-762958</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-9605-0461</idno>
                  <affiliation ref="#struct-74302"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jean-François</forename>
                    <surname>Narbonne</surname>
                  </persName>
                  <idno type="halauthorid">978011-0</idno>
                  <affiliation ref="#struct-683"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">François</forename>
                    <surname>Perin</surname>
                  </persName>
                  <idno type="halauthorid">1208797-0</idno>
                  <affiliation ref="#struct-301888"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">André</forename>
                    <surname>Picot</surname>
                  </persName>
                  <idno type="halauthorid">286990-0</idno>
                  <affiliation ref="#struct-440"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Thierry</forename>
                    <surname>Pineau</surname>
                  </persName>
                  <email type="md5">631e2286abfe0daba9b67b300236c2f9</email>
                  <email type="domain">inrae.fr</email>
                  <idno type="idhal" notation="numeric">1202623</idno>
                  <idno type="halauthorid" notation="string">155338-1202623</idno>
                  <affiliation ref="#struct-74284"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jean-François</forename>
                    <surname>Savouret</surname>
                  </persName>
                  <email type="md5">5eec0e683b3226ff98170a35081a2683</email>
                  <email type="domain">parisdescartes.fr</email>
                  <idno type="idhal" notation="numeric">834781</idno>
                  <idno type="halauthorid" notation="string">160025-834781</idno>
                  <idno type="IDREF">https://www.idref.fr/148649025</idno>
                  <idno type="VIAF">https://viaf.org/viaf/173650750</idno>
                  <idno type="ISNI">http://isni.org/isni/0000000123690049</idno>
                  <affiliation ref="#struct-18712"/>
                </author>
              </analytic>
              <monogr>
                <imprint>
                  <biblScope unit="pp">406 pages, références bibliographiques disséminées</biblScope>
                  <date type="datePub">2000</date>
                </imprint>
                <authority type="institution">Institut national de la santé et de la recherche médicale(INSERM)</authority>
              </monogr>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="fr">French</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="fr">Polluants</term>
                <term xml:lang="fr">Niveaux d’exposition</term>
                <term xml:lang="fr">Dioxines</term>
                <term xml:lang="fr">Contamination</term>
                <term xml:lang="fr">Toxicité</term>
              </keywords>
              <classCode scheme="halDomain" n="sdv.ee.sant">Life Sciences [q-bio]/Ecology, environment/Health</classCode>
              <classCode scheme="halDomain" n="sdv.spee">Life Sciences [q-bio]/Santé publique et épidémiologie</classCode>
              <classCode scheme="halTypology" n="REPORT">Reports</classCode>
              <classCode scheme="halOldTypology" n="REPORT">Reports</classCode>
              <classCode scheme="halTreeTypology" n="REPORT.RESREPORT">Reports - Research report</classCode>
            </textClass>
            <abstract xml:lang="fr">
              <p>Les dioxines regroupent deux grandes familles, les polychlorodibenzo-paradioxines(PCDD) et les polychlorodibenzofuranes (PCDF) qui font partie, comme les polychlorobiphényles (PCB) et les polybromobiphényles (PBB), de la classe des hydrocarbures aromatiques polycycliques halogénés (HAPH).Les dioxines sont des contaminants produits au cours de nombreux processus chimiques impliquant du chlore, du carbone, de l’oxygène et une température élevée. Dans les pays développés, les deux principales sources d’émission de dioxines résultent des activités d’incinération de déchets ménagers, de métallurgie et de sidérurgie. Ces émissions ont considérablement diminué au cours des dix dernières années dans ces pays. Cependant, les dioxines font partie des nombreux polluants auxquels les populations sont soumises, à de très faibles doses tout au long de leur vie.Les dioxines sont présentes dans tous les compartiments de l’écosystème (air, sols, sédiments aquatiques et marins, animaux). Très solubles dans les lipides et chimiquement stables, elles se concentrent le long de la chaîne alimentaire, et l’alimentation représente la voie majeure d’exposition pour l’homme. La possibilité d’un contrôle des aliments par la mise en place d’un plan de surveillance des produits d’origine animale, et des produits laitiers en particulier, constitue un élément important de la surveillance. La difficulté réside dans la définition, à des fins de prévention, de niveaux d’exposition tolérables (normes, valeurs guides{), qui ne peuvent être établis qu’à partir du bilan desconnaissances actuelles sur les effets toxiques des dioxines chez l’animal etchez l’homme. La compréhension du mécanisme d’action peut également contribuer à une meilleure définition du risque et en faciliter sa gestion...</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-345801" status="VALID">
          <orgName>Ecole de Santé Publique [Université Libre de Bruxelles]</orgName>
          <desc>
            <address>
              <country key="BE"/>
            </address>
            <ref type="url">https://www.ulb.ac.be/facs/esp/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-303388" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-310969" status="OLD">
          <orgName>ENSP Rennes (devenue EHESP)</orgName>
          <date type="start">1960-01-01</date>
          <date type="end">2008-01-01</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.legifrance.gouv.fr/jorf/id/JORFTEXT000000874911</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-2865" status="OLD">
          <orgName>Toxicologie Moleculaire</orgName>
          <orgName type="acronym">U490</orgName>
          <date type="start">1998-01-01</date>
          <date type="end">2005-12-31</date>
          <desc>
            <address>
              <addrLine>Centre Universitaire Des Saints Peres PARIS V 45, Rue Des Saints-Peres 75270 PARIS CEDEX 06</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-301664" type="direct"/>
            <relation name="U490" active="#struct-303623" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-3186" status="VALID">
          <idno type="ROR">https://ror.org/034yrjf77</idno>
          <orgName>Institut National de l'Environnement Industriel et des Risques</orgName>
          <orgName type="acronym">INERIS</orgName>
          <desc>
            <address>
              <addrLine>Verneuil-en-Halatte ; Nancy ; Aix en Provence</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ineris.fr/</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-172478" status="VALID">
          <orgName>Centre antipoison et de toxicovigilance (Lyon)</orgName>
          <orgName type="acronym">CAPTV Lyon</orgName>
          <desc>
            <address>
              <addrLine>Service Hospitalo-Universitaire de Pharmacologie et de Toxicologie de Lyon, Bâtiment A – 162 avenue Lacassagne, 69424 Lyon Cedex 03 – France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-lyon.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300074" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-14031" status="OLD">
          <orgName>Détoxication et réparation Tissulaire</orgName>
          <desc>
            <address>
              <addrLine>Faculté des Sciences Pharmaceutiques et Biologiques – 2 avenue du Professeur Léon Bernard – 35043 Rennes</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-105160" type="direct"/>
            <relation name="U456" active="#struct-303623" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-92863" status="VALID">
          <idno type="IdRef">026431297</idno>
          <idno type="ROR">https://ror.org/02495e989</idno>
          <orgName>Université Catholique de Louvain = Catholic University of Louvain</orgName>
          <orgName type="acronym">UCLouvain</orgName>
          <desc>
            <address>
              <addrLine>Place de l'Université 1, B-1348 Louvain-La-Neuve</addrLine>
              <country key="BE"/>
            </address>
            <ref type="url">https://www.uclouvain.be/fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300422" status="OLD">
          <orgName>Ecole Nationale Vétérinaire de Lyon</orgName>
          <orgName type="acronym">ENVL</orgName>
          <date type="end">2010</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-74302" status="VALID">
          <orgName>Center for Research in Environmental Epidemiology</orgName>
          <orgName type="acronym">CREAL</orgName>
          <desc>
            <address>
              <addrLine>Doctor Aiguader, 88 E-08003 Barcelona</addrLine>
              <country key="ES"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-128785" type="direct"/>
            <relation active="#struct-319880" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-683" status="OLD">
          <orgName>Laboratoire de Physico et Toxico-Chimie des systèmes naturels</orgName>
          <orgName type="acronym">LPTC</orgName>
          <date type="start">1997-01-01</date>
          <date type="end">2006-12-31</date>
          <desc>
            <address>
              <addrLine>351, cours de la Libération F-33405 TALENCE Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.lptc.u-bordeaux.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-92972" type="direct"/>
            <relation name="UMR5472" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-301888" status="VALID">
          <idno type="ISNI">0000 0004 0639 6384</idno>
          <idno type="ROR">https://ror.org/04t0gwh46</idno>
          <orgName>Institut Curie [Paris]</orgName>
          <desc>
            <address>
              <addrLine>26 rue d'Ulm - 75248 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://science.curie.fr/</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-440" status="OLD">
          <idno type="ISNI">0000000122863155</idno>
          <idno type="RNSR">200617587V</idno>
          <idno type="ROR">https://ror.org/02st4q439</idno>
          <orgName>Institut de Chimie des Substances Naturelles</orgName>
          <orgName type="acronym">ICSN</orgName>
          <date type="start">1959-01-01</date>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <addrLine>Avenue de la terrasse 91198 Gif-sur-Yvette cedex</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-341038" type="direct"/>
            <relation name="UPR2301" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-74284" status="OLD">
          <orgName>Laboratoire de Pharmacologie et Toxicologie</orgName>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <addrLine>180 chemin de Tournefeuille, BP93173, F-31027 Toulouse3</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.toulouse.inra.fr/pharmacologie_toxicologie/</ref>
          </desc>
          <listRelation>
            <relation name="UR66" active="#struct-92114" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-18712" status="OLD">
          <orgName>Hormones, gènes et reproduction</orgName>
          <desc>
            <address>
              <addrLine>Bat Paul Broca, 3e niveau 78 avenue du général Leclerc 94275 Le Kremlin-Bicêtre</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation name="U135" active="#struct-303623" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-303388" status="VALID">
          <idno type="IdRef">034905812</idno>
          <idno type="ISNI">0000 0001 2348 0746</idno>
          <idno type="ROR">https://ror.org/01r9htc13</idno>
          <orgName>Université libre de Bruxelles = Free University of Brussels</orgName>
          <orgName type="acronym">ULB</orgName>
          <date type="start">1970-01-01</date>
          <desc>
            <address>
              <addrLine>Avenue Franklin Roosevelt 50 - 1050 Bruxelles</addrLine>
              <country key="BE"/>
            </address>
            <ref type="url">https://www.ulb.be/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-301664" status="OLD">
          <idno type="IdRef">026404788</idno>
          <idno type="ISNI">0000 0001 2188 0914 </idno>
          <idno type="ROR">https://ror.org/0220k9r37</idno>
          <orgName>Université Paris Descartes - Paris 5</orgName>
          <orgName type="acronym">UPD5</orgName>
          <date type="start">1971-01-01</date>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <addrLine>12, rue de l'École de Médecine - 75270 Paris cedex 06</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.parisdescartes.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-303623" status="VALID">
          <idno type="IdRef">026388278</idno>
          <idno type="ROR">https://ror.org/02vjkv261</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75013 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-300074" status="VALID">
          <idno type="IdRef">026534657</idno>
          <idno type="ROR">https://ror.org/01502ca60</idno>
          <orgName>Hospices Civils de Lyon</orgName>
          <orgName type="acronym">HCL</orgName>
          <desc>
            <address>
              <addrLine>3 Quai des Célestins69002 Lyon</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-lyon.fr/fr/hospices-civils-de-lyon-hcl</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-105160" status="VALID">
          <idno type="IdRef">26693823X</idno>
          <idno type="ROR">https://ror.org/015m7wh34</idno>
          <orgName>Université de Rennes</orgName>
          <orgName type="acronym">UR</orgName>
          <desc>
            <address>
              <addrLine>Campus de Beaulieu, 263 avenue Général Leclerc, CS 74205, 35042 RENNES CEDEX</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.univ-rennes.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-128785" status="VALID">
          <idno type="ROR">https://ror.org/04n0g0b29</idno>
          <orgName>Universitat Pompeu Fabra [Barcelona]</orgName>
          <orgName type="acronym">UPF</orgName>
          <desc>
            <address>
              <addrLine>Plaça de la Mercè, 10-12 - 08002 Barcelona</addrLine>
              <country key="ES"/>
            </address>
            <ref type="url">https://www.upf.edu/en/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-319880" status="INCOMING">
          <orgName>Catalunya ministerio de salud</orgName>
          <desc>
            <address>
              <country key="ES"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-92972" status="VALID">
          <orgName>Université Sciences et Technologies - Bordeaux 1</orgName>
          <orgName type="acronym">UB</orgName>
          <date type="start">1971-01-01</date>
          <date type="end">2013-12-31</date>
          <desc>
            <address>
              <addrLine>351 cours de la Libération - 33405 Talence.</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.u-bordeaux1.fr</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-341038" status="VALID">
          <idno type="IdRef">232435103</idno>
          <idno type="ISNI">000000010626358X</idno>
          <idno type="ROR">https://ror.org/02cte4b68</idno>
          <orgName>Institut de Chimie - CNRS Chimie</orgName>
          <orgName type="acronym">INC-CNRS</orgName>
          <date type="start">2009-10-01</date>
          <desc>
            <address>
              <addrLine>CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE3 rue Michel-Ange75794 PARIS CEDEX 16 - France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.cnrs.fr/inc</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-92114" status="OLD">
          <idno type="ROR">https://ror.org/01x3gbx83</idno>
          <orgName>Institut National de la Recherche Agronomique</orgName>
          <orgName type="acronym">INRA</orgName>
          <date type="start">1946-05-18</date>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inra.fr</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>