Gait Alteration Due to Haemophilic Arthropathies in Patients with Moderate Haemophilia - l'unam - université nantes angers le mans Access content directly
Journal Articles International Journal of Environmental Research and Public Health Year : 2022

Gait Alteration Due to Haemophilic Arthropathies in Patients with Moderate Haemophilia

Abstract

Some patients with moderate haemophilia (PWMH) report joint damage potentially responsible for gait disorders. Three-dimensional gait analysis (3DGA) is a relevant tool for the identification of complex musculoskeletal impairment. We performed an evaluation with 3DGA of 24 PWMH aged 44.3 ± 16.1 according to their joint status [Haemophilia Joint Health Score (HJHS) < 10 or HJHS ≥ 10] and assessed the correlation with the radiological and clinical parameters. Sixteen had HJHS < 10 (group 1) and eight had HJHS ≥ 10 (group 2). They were compared to 30 healthy subjects of a normative dataset. Both knee and ankle gait variable scores were increased in group 2 compared to the controls (p = 0.02 and p = 0.04, respectively). The PWMH of group 2 had a significant increase in their stance phase, double support duration, and stride width compared to the controls and group 1 (p < 0.01). Very low correlations were found for the ankle gait variable score with the ankle Pettersson sub-score (r2 = 0.250; p = 0.004) and ankle HJHS sub-score (r2 = 0.150; p = 0.04). For the knee, very low correlation was also found between the knee gait variable score and its HJHS sub-score (r2 = 0.290; p < 0.0001). Patients with moderate haemophilia presented a gait alteration in the case of poor lower limb joint status.
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hal-04607534 , version 1 (10-06-2024)

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Alban Fouasson-Chailloux, Fabien Leboeuf, Yves Maugars, Marc Trossaert, Pierre Menu, et al.. Gait Alteration Due to Haemophilic Arthropathies in Patients with Moderate Haemophilia. International Journal of Environmental Research and Public Health, 2022, 19, pp.9. ⟨10.3390/ijerph19127527⟩. ⟨hal-04607534⟩
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