ATG16L1 in myeloid cells limits colorectal tumor growth in Apc Min/+ mice infected with colibactin-producing Escherichia coli via decreasing inflammasome activation
Keywords
AOM
azoxymethane APC
APC regulator of WNT signaling pathway ATG
autophagy related Atg16l1[∆MC] mice
mice deficient for Atg16l1 specifically in myeloid cells CASP1
caspase 1 BMDM
bone marrow-derived macrophage CFU
colony-forming unit CoPEC
colibactin-producing Escherichia coli CRC
colorectal cancer CXCL1/KC
C-X-C motif chemokine ligand 1 ELISA
enzyme-linked immunosorbent assay IL
interleukin MC
myeloid cell MOI
multiplicity of infection PBS
phosphatebuffered saline pks
polyketide synthase qRT-PCR
quantitative real-time reverse-transcription polymerase chain reaction siRNA
small interfering RNA TME
tumor microenvironment TNF/TNF-α
tumor necrosis factor Autophagy bacterial infection colibactinproducing E. coli colorectal cancer toxin
azoxymethane
APC
APC regulator of WNT signaling pathway
ATG
autophagy related
Atg16l1[∆MC] mice
mice deficient for Atg16l1 specifically in myeloid cells
CASP1
caspase 1
BMDM
bone marrow-derived macrophage
CFU
colony-forming unit
CoPEC
colibactin-producing Escherichia coli
CRC
colorectal cancer
CXCL1/KC
C-X-C motif chemokine ligand 1
ELISA
enzyme-linked immunosorbent assay
IL
interleukin
MC
myeloid cell
MOI
multiplicity of infection
PBS
phosphatebuffered saline
pks
polyketide synthase
qRT-PCR
quantitative real-time reverse-transcription polymerase chain reaction
siRNA
small interfering RNA
TME
tumor microenvironment
TNF/TNF-α
tumor necrosis factor Autophagy
bacterial infection
colibactinproducing E. coli
toxin
Domains
Life Sciences [q-bio]
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ATG16L1 in myeloid cells limits colorectal tumor growth in ApcMin mice infected with colibactin-producing Escherichia coli via decreasing inflammaso.pdf (8.89 Mo)
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Origin | Publication funded by an institution |
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