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Computational analysis of flow structures in turbulent ventricular blood flow associated with mitral valve intervention

Abstract : Cardiac disease and clinical intervention may both lead to an increased risk for thrombosis events due to a modified blood flow in the heart, and thereby a change in the mechanical stimuli of blood cells passing through the chambers of the heart. Specifically, the degree of platelet activation is influenced by the level and type of mechanical stresses in the blood flow. In this article we analyze the blood flow in the left ventricle of the heart through a computational model constructed from patient-specific data. The blood flow in the ventricle is modeled by the Navier-Stokes equations, and the flow through the mitral valve by a parameterized model which represents the projected opening of the valve. A finite element method is used to solve the equations, from which a simulation of the velocity and pressure of the blood flow is constructed.
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https://hal.archives-ouvertes.fr/hal-03443780
Contributeur : Didier Lucor Connectez-vous pour contacter le contributeur
Soumis le : mardi 23 novembre 2021 - 15:50:38
Dernière modification le : vendredi 5 août 2022 - 09:27:27
Archivage à long terme le : : jeudi 24 février 2022 - 19:56:08

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Computational analysis of flow...
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  • HAL Id : hal-03443780, version 1

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Joel Kronborg, Frida Svelander, Samuel Eriksson-Lidbrink, Ludvig Lindström, Carme Homs-Pons, et al.. Computational analysis of flow structures in turbulent ventricular blood flow associated with mitral valve intervention. {date}. ⟨hal-03443780⟩

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