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SARS‐CoV‐2 variants as super cell fusers: cause or consequence of COVID‐19 severity?

Abstract : The most severe forms of coronavirus disease 2019 (COVID-19) are often associated with the presence of syncytia in the lungs resulting from cell-cell fusion mediated by the SARS-CoV-2 spike protein. In this issue, Rajah and colleagues show that the SARS-CoV-2 alpha, beta, and delta variants promote enhanced syncytia formation as compared to the original strain.
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https://hal.inrae.fr/hal-03521122
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Submitted on : Tuesday, January 11, 2022 - 1:53:19 PM
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Jana Koch, Zina Uckeley, Pierre-Yves Lozach. SARS‐CoV‐2 variants as super cell fusers: cause or consequence of COVID‐19 severity?. EMBO Journal, EMBO Press, 2021, 40 (24), ⟨10.15252/embj.2021110041⟩. ⟨hal-03521122⟩

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