Abstract : The most severe forms of coronavirus disease 2019 (COVID-19) are often associated with the presence of syncytia in the lungs resulting from cell-cell fusion mediated by the SARS-CoV-2 spike protein. In this issue, Rajah and colleagues show that the SARS-CoV-2 alpha, beta, and delta variants promote enhanced syncytia formation as compared to the original strain.
https://hal.inrae.fr/hal-03521122 Contributor : Sabine ROSSIConnect in order to contact the contributor Submitted on : Tuesday, January 11, 2022 - 1:53:19 PM Last modification on : Tuesday, May 31, 2022 - 11:34:02 AM Long-term archiving on: : Tuesday, April 12, 2022 - 7:08:13 PM
Jana Koch, Zina Uckeley, Pierre-Yves Lozach. SARS‐CoV‐2 variants as super cell fusers: cause or consequence of COVID‐19 severity?. EMBO Journal, EMBO Press, 2021, 40 (24), ⟨10.15252/embj.2021110041⟩. ⟨hal-03521122⟩