With over 20 years of experience, the GenomEast platform offers a wide range of services to explore genomes, their expression and regulation, from quality control of starting samples to data analysis. These services are intended for the entire scientific community, national and international, public and private.
Recent publications
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Nicolas Dupré, Florian Gueniot, Valérie Domenga-Denier, Virginie Dubosclard, Christelle Nilles, et al.. Protein aggregates containing wild-type and mutant NOTCH3 are major drivers of arterial pathology in CADASIL Authors. The Journal of clinical investigation, 2024, ⟨10.1172/JCI175789⟩. ⟨inserm-04504015⟩
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Christophe Papin, Abdulkhaleg Ibrahim, Jamal Sabir, Stéphanie Le Gras, Isabelle Stoll, et al.. MBD4 loss results in global reactivation of promoters and retroelements with low methylated CpG density. Journal of experimental & clinical cancer research, 2023, 42 (1), pp.301. ⟨10.1186/s13046-023-02882-z⟩. ⟨hal-04288047⟩
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Hélène Neyret-Kahn, Jacqueline Fontugne, Xiang Yu Meng, Clarice Groeneveld, Luc Cabel, et al.. Epigenomic mapping identifies an enhancer repertoire that regulates cell identity in bladder cancer through distinct transcription factor networks. Oncogene, 2023, 42 (19), pp.1524-1542. ⟨10.1038/s41388-023-02662-1⟩. ⟨hal-04092965⟩
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Quentin Raas, Ali Tawbeh, Mounia Tahri-Joutey, Catherine Gondcaille, Céline Keime, et al.. Peroxisomal defects in microglial cells induce a disease-associated microglial signature. Frontiers in Molecular Neuroscience, 2023, 16 (Sec. Brain Disease Mechanisms), pp.1170313. ⟨10.3389/fnmol.2023.1170313⟩. ⟨hal-04092819⟩