Skip to Main content Skip to Navigation
Conference papers

Infering an ontology of single cell motions from high-throughput microscopy data

Abstract : Cellular motility is a fundamental biological process. Progress in the fields of gene silencing and high-throughput (HT) microscopy provide us with the tools to study its molecular basis and potential perturbators. The primary contribution of this paper is to present MotIW, a generic workflow for single cell motility study in HT time-lapse screening data. We successfully apply it to a simulated screen, as well as a genome-wide screen. Furthermore, MotIW enables the identification of eigth motility patterns into which all trajectories from this dataset divide up into, without any prior model of cell motion.
Document type :
Conference papers
Complete list of metadatas

Cited literature [10 references]  Display  Hide  Download

https://hal.inrae.fr/hal-02742630
Contributor : Migration Prodinra <>
Submitted on : Tuesday, November 17, 2020 - 6:23:05 PM
Last modification on : Friday, November 27, 2020 - 3:46:04 PM

File

SchoenauerSebag2015.pdf
Files produced by the author(s)

Licence


Distributed under a Creative Commons Attribution 4.0 International License

Identifiers

Citation

Alice Schoenauer Sebag, Sandra Plancade, Céline Raulet-Tomkiewicz, Robert Barouki, Jean-Philippe Vert, et al.. Infering an ontology of single cell motions from high-throughput microscopy data. IEEE 12th International Symposium on Biomedical Imaging, Apr 2015, New York, United States. pp.4, ⟨10.1109/ISBI.2015.7163840⟩. ⟨hal-02742630⟩

Share

Metrics

Record views

98

Files downloads

46